基本资料

姓名：吴睿

职称：特聘副教授

所在系：有机化学

研究方向：不对称催化、金属卡宾化学、炔烃化学

办公室：19号楼709室

电子邮件：wurui@zstu.edu.cn

教育工作经历

2012-2016 广东工业大学轻工化工学院，化工学士

2016-2021 华南理工大学化学与化工学院，有机化学博士

2022-2024 华南理工大学化学与化工学院，博士后

2024.06至今 浙江理工大学，特聘副教授

研究兴趣：炔烃的不对称转化、双核铑化学、卡宾化学

个人获奖：中国化学会手性中国2021（2022）学术研讨会Presentation Prize;国家奖学金、华南理工大学校长奖学金等

科研项目

1、 国家自然科学基金青年项目（主持），2023.01-2025.12

2、 浙江省自然科学基金（主持），2025.01-2026.12

3、 浙江省青年托举人才项目（主持），2025.01-2027.12

4、 中国博士后面上项目（主持），2023.01-2024.05

5、 广州市基础与应用基础研究项目（主持），2023.04-2025.03

科研成果

1. Chuntao Wang, Zi-Hao Liao, Rui Wu*, Kai Chen*, Shifa Zhu*. Enantioselective Synthesis of 1-Dihydrobenzazepines through Rh2(II)-Catalyzed Cycloisomerization of 1,6-Enyne. J. Am. Chem. Soc. 2025, DOI: 10.1021/jacs.5c00053.

2. Rui Wu, Zurong Xu, Dong Zhu, Shifa Zhu*. Dirhodium-Catalyzed Asymmetric Transformations of Alkynes via Carbene Intermediates. Acc. Chem. Res. 2025, 58, DOI: 10.1021/acs.accounts.4c00715.

3. Zurong Xu, Dong Zhu, Rui Wu*, Shifa Zhu*. Tandem Rh(II)-catalyzed 1,3-acyloxy migration/intermolecular [2+2] cycloaddition of electronically deficient propargylic esters with alkenes and alkynes. Chem. Sci. 2025, 16, 205-210.

4. Xiang Gao, Wendeng Li, Yang Chen, Rui Wu*, Shifa Zhu*. Dirhodium-Catalyzed [2+2+2] Cycloaddition of 1,6-Diynes and Alkynes. J. Org. Chem. 2024, 89, 17248-17259.

5. Zurong Xu, Jiajun Lu, Huanfeng Jiang, Rui Wu*, Shifa Zhu*. Dirhodium(II)-catalyzed regio- and stereoselective cycloisomerization towards 6,5,3-tricyclic skeletons containing vicinal all-carbon quaternary stereocenters. Org. Chem. Front. 2024, 11, 5151

6. Chuntao Wang, Dong Zhu, Rui Wu* and Shifa Zhu*. Dirhodium-catalyzed enantioselective synthesis of difluoromethylated cyclopropanes via enyne cycloisomerization. Adv. Sci. 2024, 11, 2306404.

7. Rui Wu, Yang Chen, Shifa Zhu*. Rh(II)-Catalyzed Enynal Cycloisomerization for Generation of Vinyl Carbene: Divergent Access to Polycyclic Heterocycles. ACS Catal. 2023, 13, 132.

8. Rui Wu, Dong Zhu, Shifa Zhu*. Dirhodium: Carbene Transformations and Beyond. Org. Chem. Front. 2023, 10, 2849.

9. Rui Wu, Jiajun Lu, Tongxiang Cao, Jun Ma, Kai Chen* and Shifa Zhu*. Enantioselective Rh(II)-Catalyzed Desymmetric Cycloisomerization of Diynes: Constructing Furan-Fused Dihydropiperidines with an Alkyne-Substituted Aza-Quaternary Stereocenter. J. Am. Chem. Soc. 2021, 143, 14916.

10. Rui Wu, Kai Chen, Jun Ma, Zhi-Xiang Yu* and Shifa Zhu*. Synergy of Activating Substrate and Introducing C-H···O Interaction to Achieve Rh2(II)-Catalyzed Asymmetric Cycloisomerization of 1,n-Enynes. Sci. China Chem. 2020, 63, 1230.

11.  Wendeng Li, Rui Wu, Hao Ruan, Bo Xiao, Xiang Gao, Huanfeng Jiang, Kai Chen, Tian-Yu Sun*, and Shifa Zhu*. Axial Ligand Enables Synthesis of Allenylsilane through Dirhodium(II) Catalysis. Angew. Chem. Int. Ed. 2024, 63, e202409332.

12.  Chuntao Wang, Rui Wu, Kai Chen*, Shifa Zhu*. Enantioselective Synthesis of Biscyclopropanes Using Alkynes as Dicarbene Equivalents. Angew. Chem. Int. Ed. 2023, 62, e202305864.

13.  Tairan Cheng, Boxiang Liu, Rui Wu and Shifa Zhu*, Cu-Catalyzed Carboboration of Acetylene with Michael Acceptors. Chem. Sci. 2022, 13, 7604.